WANG Zun-yuan, LIANG Mei-hao, MA Zhen, SHEN Zheng-rong. New preparation of(S)-(+)-flurbiprofen[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (6): 463-465.
Citation:
WANG Zun-yuan, LIANG Mei-hao, MA Zhen, SHEN Zheng-rong. New preparation of(S)-(+)-flurbiprofen[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (6): 463-465.
WANG Zun-yuan, LIANG Mei-hao, MA Zhen, SHEN Zheng-rong. New preparation of(S)-(+)-flurbiprofen[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (6): 463-465.
Citation:
WANG Zun-yuan, LIANG Mei-hao, MA Zhen, SHEN Zheng-rong. New preparation of(S)-(+)-flurbiprofen[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (6): 463-465.
OBJECTIVE To synthesize S-enantiomer of non-steroids anti-inflammation drug flurbiporfen.METHODS 2-Fluoroaniline was brominated with 1,3-dibromo-5,5-dimethylhydantoin,then condensed with benzene to give 2-fluoro-4-bromo-biphenyl,which reacted with sodium
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