ZHAO Yu-song, CHEN Bao-quan, ZHANG Di-qun. Improved Synthesis of 4-guanidinobenzoic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 120-121.
Citation:
ZHAO Yu-song, CHEN Bao-quan, ZHANG Di-qun. Improved Synthesis of 4-guanidinobenzoic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 120-121.
ZHAO Yu-song, CHEN Bao-quan, ZHANG Di-qun. Improved Synthesis of 4-guanidinobenzoic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 120-121.
Citation:
ZHAO Yu-song, CHEN Bao-quan, ZHANG Di-qun. Improved Synthesis of 4-guanidinobenzoic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 120-121.
OBJECTIVE To improve the synthetic process of 4-guanidinobenzoic acid.METHODS By this method,iodomethane was replaced with bromoethane.RESULTS The overall yield was 60.9%.CONCLUSION The process is simple and suitable for industrial production.
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