Evaluation of arginine esterase from Agkistrodon halys ussuriensis venom for gene mutation in Ames test

OBJECTIVE To investigate the gene mutagenesis of arginine esterase from Agkistrodon halys ussuriensis venom. METHOD The Salmaonella typhimurium/mammalian microsomal test (Ames Test) was conducted using histidine requiring Salmonella typhimurium indicato