A study on the synthesis of a new antitumor drug-Exemestane
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Graphical Abstract
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Abstract
OBJECTIVE:To modify the synthetic method of the new antitumor drug-Exemestane. METHOD:Exemestane was synthesized by steps of Oppenauer oxidation, methylenation and dehydrogenation, starting from 5-Epiandrostane-17-one. RESULTS:The chemical structure of sy
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