Liu Tao, Yao Aiping, Hu Yongzhong. A study on the synthesis of a new antitumor drug-Exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (5): 359-361.
Citation:
Liu Tao, Yao Aiping, Hu Yongzhong. A study on the synthesis of a new antitumor drug-Exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (5): 359-361.
Liu Tao, Yao Aiping, Hu Yongzhong. A study on the synthesis of a new antitumor drug-Exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (5): 359-361.
Citation:
Liu Tao, Yao Aiping, Hu Yongzhong. A study on the synthesis of a new antitumor drug-Exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (5): 359-361.
A study on the synthesis of a new antitumor drug-Exemestane
OBJECTIVE:To modify the synthetic method of the new antitumor drug-Exemestane. METHOD:Exemestane was synthesized by steps of Oppenauer oxidation, methylenation and dehydrogenation, starting from 5-Epiandrostane-17-one. RESULTS:The chemical structure of sy