Xu Jun(Xu J), Chai Yuzhu(Chai YZ), Yan Xiangping(Yan XP), Ye Huimin(Ye HM), Wang Puhai(Wang PH), Leng Zongkang(Leng ZK). Synthesis of aromatase inhibitor exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (1): 44-46.
    Citation: Xu Jun(Xu J), Chai Yuzhu(Chai YZ), Yan Xiangping(Yan XP), Ye Huimin(Ye HM), Wang Puhai(Wang PH), Leng Zongkang(Leng ZK). Synthesis of aromatase inhibitor exemestane[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (1): 44-46.
    • OBJECTIVE: To synthesize exemestane and optimize the process. METHOD: This compound was synthesized by steps of Mannich reaction, bromination, and debromination. RESULT: Chemical structure of the product was conformed by element analysis, UV, IR,1HNMR, an
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