Synthesis of 3,4-2H-6-chlorobenzopyran-4-one

Xiong XY, Zou Y, Mei QB, Zhao DH. Synthesis of 3,4-2H-6-chlorobenzopyran-4-one[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (1): 41-42.

Citation:

Xiong XY, Zou Y, Mei QB, Zhao DH. Synthesis of 3,4-2H-6-chlorobenzopyran-4-one[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (1): 41-42.

Citation:

Xiong XY, Zou Y, Mei QB, Zhao DH. Synthesis of 3,4-2H-6-chlorobenzopyran-4-one[J]. Chinese Journal of Modern Applied Pharmacy, 2002, (1): 41-42.

Abstract

OBJECTIVE: To synthesize 3,4-2H-6-chlorobenzopyran-4-one, a key intermediate for the preparation of oxa nonsteroidal estrogen analogues. METHODS: 3,4-2H-6-chlorobenzopyran-4-one was synthesized by reactions of nucleophilic addition, hydrolyzation and cyc

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