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    Han Guang(Han G), Han Baolai(Han BL). Synthisis of 5-methylprazine-2-carboxylic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2000, (3): 208-210.
    Citation: Han Guang(Han G), Han Baolai(Han BL). Synthisis of 5-methylprazine-2-carboxylic acid[J]. Chinese Journal of Modern Applied Pharmacy, 2000, (3): 208-210.
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    Synthisis of 5-methylprazine-2-carboxylic acid

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    • OBJECTIVE:To synthesize 5- methylpyrazine-2-carboxylic acid.METHOD:5-methylpyrazine-2-carboxylic acid was synthesized from 2,5-dimethylpyrazine and N-chlorosuccinimide by chlorinating,esterification,alkalisis and oxidation.RESULTS:The yield of the 5-methy
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