Wang Lichen(Wang LC), Ren Jinzhi(Ren JZ), Wei Wanwu(Wei WW) et al, . Improved synthesis of celiprolol hydrochloride[J]. Chinese Journal of Modern Applied Pharmacy, 1998, (6): 35-36.
Citation:
Wang Lichen(Wang LC), Ren Jinzhi(Ren JZ), Wei Wanwu(Wei WW) et al, . Improved synthesis of celiprolol hydrochloride[J]. Chinese Journal of Modern Applied Pharmacy, 1998, (6): 35-36.
Wang Lichen(Wang LC), Ren Jinzhi(Ren JZ), Wei Wanwu(Wei WW) et al, . Improved synthesis of celiprolol hydrochloride[J]. Chinese Journal of Modern Applied Pharmacy, 1998, (6): 35-36.
Citation:
Wang Lichen(Wang LC), Ren Jinzhi(Ren JZ), Wei Wanwu(Wei WW) et al, . Improved synthesis of celiprolol hydrochloride[J]. Chinese Journal of Modern Applied Pharmacy, 1998, (6): 35-36.
OBJECTIVE: Synthesis of celiprolol hydrochloride and the improvement of the process. METHODS:Abolishing of brominating step and optimizing of etherifying reaction. RESULTS: Synthetic route was shorten by one step, the yield of etherification increased by