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    Fu Xu-chun, Li Guang-hua. Study on the Structure-activity Relationships of 6, 8-difluoroquinolone Antibacterials[J]. Chinese Journal of Modern Applied Pharmacy, 1997, (1): 31-33.
    Citation: Fu Xu-chun, Li Guang-hua. Study on the Structure-activity Relationships of 6, 8-difluoroquinolone Antibacterials[J]. Chinese Journal of Modern Applied Pharmacy, 1997, (1): 31-33.
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    Study on the Structure-activity Relationships of 6, 8-difluoroquinolone Antibacterials

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    • The structure-activity relationships of ten 6, 8-difluoroquinolones, have been studidd.The results showed that the N1-substitutent,should be lipophilic in addition to adapt theoptimal STERIMOL length. C7-substitutent affected the antibacterial activity of
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