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    Wang Li-chen et al, . Improved Process of Synthesis on Pyracetam[J]. Chinese Journal of Modern Applied Pharmacy, 1997, (1): 29-30.
    Citation: Wang Li-chen et al, . Improved Process of Synthesis on Pyracetam[J]. Chinese Journal of Modern Applied Pharmacy, 1997, (1): 29-30.
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    Improved Process of Synthesis on Pyracetam

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    • 2-pyrolidone and methyl chlotoacetate were used as starting materials via twosteps: condensation and ammonolysis to yield pyracetam. The total yield of pyracetam is 66%.Orthogonal design and Uniform design were used in the synthesis.
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