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    Ruan ZR, Dian DY. HPLC Method for Determination of Phenytoin and its Metabolite 4'-Hydroxyphenytoin in Human Urine[J]. Chinese Journal of Modern Applied Pharmacy, 1993, (1): 20-23.
    Citation: Ruan ZR, Dian DY. HPLC Method for Determination of Phenytoin and its Metabolite 4'-Hydroxyphenytoin in Human Urine[J]. Chinese Journal of Modern Applied Pharmacy, 1993, (1): 20-23.
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    HPLC Method for Determination of Phenytoin and its Metabolite 4'-Hydroxyphenytoin in Human Urine

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    • A RH-HPLC procedure had been developed for the determination of phenytoin(PHT)and its main metabolite 4'-hydroxyphenytoin(HPPH)in human urine.PHT and HPPH were extr-acted from urine using ether. HPLC was performed on a Bio-Sil(?) ODS column,with a mobilep
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