Study on the Extractive Technology of Qishen Jiangu Granules

OBJECTIVE To optimize the extractive technology of Qishen Jiangu granules. METHODS The single-factor experiment and orthogonal experiment were used to determine the optimal conditions including granularity of medicine, sunk time, solvent amount, extraction time and times with the transfer rates of astragaloside IV and salvianolic acid B as the index, and multi-index score method (weight coefficient: astragaloside IV∶salvianolic acid B=0.6∶0.4). RESULTS The optimized conditions were determined as follows: the sunk time was 1 h, 12 times volumn of water was used to extract medicine decoction pieces for 3 times, extraction time was 0.5 h. CONCLUSION The optimized process is feasible, stable and replicable.