Determination of Residual Organic Solvents in Di--butyl-(2,6-difluorobenzohydroxamato) Tin(IV) by GC

OBJECTIVE To develop a method for the determination of residual organic solvents in Di-n-butyl- (2,6-difluorobenzohydroxamato)Tin(IV). METHODS The capillary gas chromatography method was established with FID detector and DB-1 capillary column with 50 ℃. The temperature at the injector and the detector were 200 ℃ and 220 ℃, respectively. The carrier gas was nitrogen with a flow rate of 2.0 mL·min^-1. The split ratio was 50∶1. The 1,2-dichloroethane was used as the internal standard to determine the residual organic solvents. RESULTS Methanol, N-hexane and methylbenzene showed a linear range within 9-375 μg·mL^-1(r=0.999 8), 0.87-36.25 μg·mL^-1(r=0.999 7), 2.67-111.25 μg·mL^-1 (r=0.999 8), respectively. The average recoveries were 99.1%(RSD=2.5%), 98.3%(RSD=2.7%), 99.7%(RSD=1.3%), respectively. CONCLUSION The method was rapid, simple, accurate and suitable for the analysis of residual organic solvents in Di-n-butyl- (2,6-difluorobenzohydroxamato) Tin(IV).