JIN Min, CUI Yulong, LI Mengqi, SHI Yu, ZHOU Quanying, LI Lingjun. Research Progress on Structure, Pharmacological Action and Mechanism of Ganoderic Acid[J]. Chinese Journal of Modern Applied Pharmacy, 2025, 42(3): 500-510. DOI: 10.13748/j.cnki.issn1007-7693.20233268
    Citation: JIN Min, CUI Yulong, LI Mengqi, SHI Yu, ZHOU Quanying, LI Lingjun. Research Progress on Structure, Pharmacological Action and Mechanism of Ganoderic Acid[J]. Chinese Journal of Modern Applied Pharmacy, 2025, 42(3): 500-510. DOI: 10.13748/j.cnki.issn1007-7693.20233268

    Research Progress on Structure, Pharmacological Action and Mechanism of Ganoderic Acid

    • Ganoderma lucidum, as a well-known Chinese fungal traditional Chinese medicine, has the effect of invigorating Qi and calming nerves, relieving cough and relieving asthma. Ganoderic acid is one of the main active components of Ganoderma lucidum. It has many pharmacological effects, such as anti-inflammation, anti-tumor, anti-aging, protection of nervous system and cardiomyocytes, improvement of organ damage, regulation of glucose and lipid metabolism, etc. It has good effects in the treatment of inflammation, cancer and nervous system-related diseases. In this paper, the structure and pharmacological action of ganoderic acid were reviewed, and the pharmacological mechanism of ganoderic acid was elucidated, so as to provide reference for its clinical application and new drug development.
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