Analysis on Chemical Constituents from the Seeds of Celosia Cristata L. by UPLC-ESI-Q-TOF-MS

OBJECTIVE To qualitatively analyse the chemical constituents from the seeds of Celosia cristata L. based on UPLC-ESI-Q-TOF-MS.

METHODS The mass spectrum data were collected by UPLC-ESI-Q-TOF-MS. The data were analyzed by precise molecular weight and fragment ion information provided by high-resolution mass spectrometry, combined with SciFinder database, relevant literatures of Celosia, reference materials and mass fragmentation patterns.

RESULTS A total of 76 compounds were identified from the seeds of Celosia cristata, including 13 cyclopeptides, 18 triterpenoids, 16 flavonoids, 11 phenols, 6 phenylpropanoids, 4 steroids, and 8 other compounds. Among them, 27 compounds were reported for the first time from this species. And this study explored the mass fragmentation pattern of Urticaceae-type cyclopeptides and Solanaceae-type cyclopeptides for the first time.

CONCLUSION The study provides a quick, accurate, comprehensive analysis of chemical constituents in the seeds of Celosia cristata, and so as to provide a scientific basis for the clarification of quality control and pharmacodynamical material basis with the seeds of Celosia cristata.