YANG Chen, ZHANG Bin, CHEN Caojuan, LIU Ping'an, PENG Yanmei, TAN Qunying, LI Yuehui. Research Progress of Deinagkistrodon Acutus Venom[J]. Chinese Journal of Modern Applied Pharmacy, 2023, 40(23): 3324-3333. DOI: 10.13748/j.cnki.issn1007-7693.20230099
    Citation: YANG Chen, ZHANG Bin, CHEN Caojuan, LIU Ping'an, PENG Yanmei, TAN Qunying, LI Yuehui. Research Progress of Deinagkistrodon Acutus Venom[J]. Chinese Journal of Modern Applied Pharmacy, 2023, 40(23): 3324-3333. DOI: 10.13748/j.cnki.issn1007-7693.20230099

    Research Progress of Deinagkistrodon Acutus Venom

    • Deinagkistrodon acutus(also known as the five-paced viper and the traditional Chinese medicine ingredient is called Agkistrodon) venom is a viscous liquid from the venom glands of the Deinagkistrodon acutus. It contains a variety of protein and peptide components such as phospholipase A2, serine protease, metalloproteinase, C-type lectin, L-amino acid oxidase, and has a variety of biological activities, playing an important role in anti-tumour, anti-thrombotic, anti-inflammatory and anti-bacterial activities. In recent years, snake venom research has become increasingly widespread, but there is still a lack of comprehensive and systematic studies on snake venom from Deinagkistrodon acutus. In this paper, the source, identification, active ingredients, toxicity studies and quality researches of Deinagkistrodon acutus venom are summarized and analysed by searching the related research progress, in order to provide reference for further development and utilization of Deinagkistrodon acutus venom.
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