Experience in the Design and Implementation of Randomized Controlled Trials

Randomized controlled trial is one of the most important types of medical research. Scientific design and standardized implementation are important prerequisites to ensure the authenticity and reliability of research results. The author briefly summarized the key points of RCT, such as research endpoint, sample size estimation, randomization and allocation concealment, blinding, analysis set, interim analysis, registration, data management and research reporting. By sharing practical experience, this paper provided help for beginners of clinical research.