Comparison of Process Technology for Perillae Fructus Formula Granules with Different Pretreatment Processes

OBJECTIVE To study the effect of different pretreatment process on production process of Perillae Fructus formula granules.METHODS The content of active ingredients,fingerprint,extraction rate,feasibility of the process and quality of finished products were taken as indicators to evaluate the effect of different pretreatment process on formula granules.RESULTS The extract of Perillae Fructs after grinding had a lot of fat oil,which could not meet the requirements of formula granule preparation.Although the content of index components in the extract without grinding decreased,but it fully met the relevant requirements,and the formula granules could be successfully prepared.CONCLUSION In the development of formula granules,the fruit seed medicinal materials to be comminution or not should according to the specific conditions,which can not be generalized.