Research Advances of Reductive Stress in Cardiovascular Diseases

Reductive stress can regulate the ability of redox to regulate epigenetic modification, it has received more and more attention in recent years. Reductive stress represents an imbalance of redox homeostasis as a non-specific response, which is harmful to biological systems. Reductive stress is mainly manifested as an increase in reduction equivalent. In recent years, it has been found that reduction stress is closely related to the occurrence and development of cardiovascular diseases, and has a promising application prospect in the treatment of cardiovascular diseases. However, the specific role of reductive stress in these cardiovascular diseases is not completely clear, including novel biomarkers and new way to achieve precision medicine. This review briefly introduced reductive stress and the latest research developments in the occurrence and development of different cardiovascular diseases, expecting to provide references on the clinical practice of reductive stress for cardiovascular related diseases.