Research Progress on the Mechanism of Vitexin in Preventing and Treating Diseases

Vitexin is a natural flavonoid. It has strong antioxidant properties, can effectively remove oxygen free radicals in the body, can improve blood circulation, reduce cholesterol, and inhibit exudation of inflammatory organisms enzymes. It also has anti-myocardial infarction, antibacterial, antitumor and other pharmacological effects, therefore, it is currently used in the protection and treatment of major diseases. This article reviews the mechanism of vitexin treatment of various diseases through regulating, mitochondrial pathway, MAPK pathway, AKT pathway, autophagy ability and related apoptotic proteins(p53, Bcl-2, Bax and caspase etc.), and prospects the application prospects of vitexin.