Research Progress of 3D Printing Technology in Oral Solid Preparations
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Graphical Abstract
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Abstract
Oral solid preparations are the most common dosage forms for clinical medication. 3D printing technology can accurately control the internal composition and external shape of oral solid preparations through computer-aided design, thereby controlling drug release performance and achieving precise treatment. In recent years, various 3D printed oral solid preparations have been developed, with different properties including rapid-release, slow-release and Chinese medicine compound etc., to improve the efficacy of traditional oral solid medicines. With the development of precision therapy, 3D printed pharmaceutical preparations have gradually become one of the research hotspots. At the same time, 3D printing, as an emerging science and technology, has some shortcomings, which urgently need to be solved by researchers. This article reviews the classification of 3D printing technology and its applications, and further analyzes the opportunities and challenges encountering in the future, which provides a valid reference for the research and application of 3D printing technology in oral solid preparations, and proposes new ideas and technologies for clinical personalized drug delivery.
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