Pharmaceutical Practice of Clinical Pharmacist for A Patient with Hyperlipidemic Acute Pancreatitis During Pregnancy

OBJECTIVE To explore the role of clinical pharmacist in the formulation of therapy plan and pharmaceutical care for a patient with hyperlipidemic acute pancreatitis during pregnancy. METHODS According to the change of a patient's condition, clinical pharmacist provided pharmaceutical care throughout the therapy of the pregnant patient with hyperlipidemic acute pancreatitis in General Hospital of Ningxia Medical University, assisted physician to optimize medication plan, including the lipid lowering agents, anti-infection regimens and analgesic drugs in terms of the timing, safety and effectiveness of drug selection, and to carry out pharmaceutical monitoring. RESULTS According to the blood lipids level, fenofibrate and atorvastatin calcium were used to lower lipids, coorperated with low-molecular-weight heparin. Clinical pharmacist suggested the use of pethidine hydrochloride to control the abdominal pain. The antibiotics was upgraded from piperacillin/tazobactam to meropenem when the infection was aggravated, de-escalated to ceftazidime and metronidazole after infection improved, and stopped in time when infection well controlled. The physician adopted the recommendations. The laboratory indicators turned to normal, abdominal pain improved, blood lipids decreased significantly, the cesarean section was successfully performed, and transferred to gastroenterology department. CONCLUSION When it comes to pregnant patient, clinical pharmacists should evaluate the necessity of medication in accordance with the severity of the disease, then exert specialty advantages in assist physicians to formulate therapy plan, provide pharmaceutical care to guarantee the safety and effectiveness of medication.