Study on Therapeutic Effect of Wenjing Tongbaoyin Combined with Hysteroscopy on Patients with Oviduct Obstructive Infertility

OBJECTIVE To explore the effect of Wenjing Tongbaoyin combined with hysteroscopy on patients with oviduct obstructive infertility. METHODS From May 2017 to May 2019, 66 cases of infertile tubal obstructive infertility(cold blood stasis type) patients who were hospitalized in the gynecology department of The First Affiliated Hospital of Henan University of CM and received oviduct recanalization by hysteroscopy combined surgery. A simple random method was used to divide into 2 groups, the control group was given conventional treatment, and the observation group was given conventional treatment+Wenjing Tongbaoyin treatment. The treatment effect, oviduct patency, pregnancy, adverse reactions and inflammatory indexs and hemorheology indexs before and after treatment were compared between the two groups. RESULTS The effective rate of treatment in the two groups was 66.67% and 93.94%, respectively, and the effective rate in the observation group was higher than that in the control group(P<0.05). There was a statistically significant difference between the two groups after treatment of the fallopian tube patency(P<0.05). The observation group had a higher oviduct patency rate than the control group. The rate of intrauterine pregnancy in the observation group was higher than that in the control group, and the rate of infertility was lower than that in the control group(P<0.05); there was no statistical difference in the rate of ectopic pregnancy between the two groups. The levels of interleukin(IL-6), tumor necrosis factor-α(TNF-α), plasma viscosity, high shear whole blood viscosity and low shear whole blood viscosity after treatment in the two groups were lower than those before treatment(P<0.05); The levels of IL-6, TNF-α, plasma viscosity, high shear whole blood viscosity and low shear whole blood viscosity after treatment in the observation group were lower than those in the control group(P<0.05). No adverse reactions occurred during treatment in both groups. CONCLUSION The application of Wenjing Tongbaoyin combined with hysteroscopy in oviduct obstructive infertility can improve the therapeutic effect, increase the pregnancy rate and improve the body's inflammatory state and hemorheology.