Study on Improvement and Promotion of Quality Standard of Fuzi Lizhong Pills

OBJECTIVE To improve and upgrad the quality standard of Fuzi Lizhong pills. METHODS TLC was used for improving qualitative identification of dried ginger in the preparation, adding qualitative identification of codonopsis, and alabaster Ⅰ and alabaster Ⅲ from Baizhu. The contents of 6-gingerol in Zingiberis Rhizoma and 4 kinds of sugar components in honey were determined by HPLC. RESULTS The TLC Chart showed clear spots and strong specificity. The 6-gingerol showed a good linear relationship in the linear range of 0.04-0.30 mg(r=0.998 6), the average recovery rate was 99.43%, and RSD was 1.5%(n=9). The calibration curves of fructose, D-anhydrous glucose, sucrose, maltose showed a good linear relationship over the range of 75.003 0-375.015 0 μg(r=1.000 0), 80.001 5-400.007 5 μg(r=1.000 0), 10.056 0-50.030 0 μg(r=0.999 3), 10.055 0-50.275 0 μg (r=0.994 4). The average recovery rate were 100.03%, 99.34%, 94.66%, 97.46% with RSD of 1.33%, 1.42%, 1.25%, 0.46%. CONCLUSION The improved and upgraded quality standard is scientific and feasible, and can be used for the quality control of Fuzi Lizhong pills.