Whole-course Pharmaceutical Care of a Patient with Antibiotic-associated Diarrhea

OBJECTIVE To explore the therapeutic strategy of antibiotic-associated diarrhea(AAD) and the work significance of clinical pharmacists. METHODS Pharmaceutical care was given to a patient with AAD who was participated by clinical pharmacist during the whole course of drug treatment and other drugs in use, and reasonable drug use suggestions were put forward. RESULTS The patient with AAD was insensitive to vancomycin and antibiotics could not be stopped, clinical pharmacist suggested adding trimebutine tablets and bifidobacterium triple viable capsules, combined with montmorillonite powder and licheniform bacillus viable capsules, and diarrhea symptoms improved; during the anti-infective treatment with cefoperazone/sulbactam, clinical pharmacist recommend that vitamin K should be used to prevent bleeding; metoprolol sustained-release tablets(betaloc) that patient need to take for a long time could be administered by gastric tube. CONCLUSION The reactivity of non-clostridium difficile or non-infectious AAD to vancomycin is not clear, but anti-peristaltic agents may be effective. More studies are needed to confirm the value of vitamin K as a preventive measure during cefoperazone administration. Clinical pharmacists shall pay close attention to the details of drug use, give full play to their professional advantages, and provide high quality and personalized pharmaceutical care for patients.