LI Man, REN Jinmei, XIE Ning. Meta-analysis of Effect of Sodium Tanshinone ⅡA Sulfonate Combined with Western Medicine in Treating Unstable Angina Pectoris[J]. Chinese Journal of Modern Applied Pharmacy, 2020, 37(14): 1740-1746. DOI: 10.13748/j.cnki.issn1007-7693.2020.14.014
    Citation: LI Man, REN Jinmei, XIE Ning. Meta-analysis of Effect of Sodium Tanshinone ⅡA Sulfonate Combined with Western Medicine in Treating Unstable Angina Pectoris[J]. Chinese Journal of Modern Applied Pharmacy, 2020, 37(14): 1740-1746. DOI: 10.13748/j.cnki.issn1007-7693.2020.14.014

    Meta-analysis of Effect of Sodium Tanshinone ⅡA Sulfonate Combined with Western Medicine in Treating Unstable Angina Pectoris

    • OBJECTIVE To evaluate the efficacy and safety of sodium tanshinone ⅡA sulfonate injection in the treatment of unstable angina pectoris. METHODS Randomized controlled trials of sodium tanshinone ⅡA sulfonate injection for the treatment of unstable angina pectoris were performed with the database by computer, used modified Jadad scoring method for quality evaluation and used Revman5.3 for meta-analysis for each outcome. RESULTS A total of 27 studies of meta-analysis showed that the total effective rate of unstable angina pectoris, ECG improvement rate and plasma viscosity improvement in the treatment group of sodium tanshinone ⅡA sulfonate injection were superior to conventional treatment group. CONCLUSION Based on the current evidence, adjuvant therapy of sodium tanshinone ⅡA sulfonate injection can achieve better clinical efficacy in the treatment of unstable angina pectoris, with low adverse reactions rate.
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