Establishment and Application Analysis of Evaluation Standard for Clinical Application of Meropenem in Pediatrics

OBJECTIVE To establish clinical application evaluation criteria for meropenem in pediatrics, analyze and evaluate the current status of clinical use for this drug. METHODS Based on meropenem instruction, combined with the characteristics of clinically relevant infections in pediatrics, as well as related infectious disease guidelines and expert consensus, clinical application evaluation criteria for meropenem in pediatrics was established. A retrospective study was used to analyze and evaluate the clinical application status of 232 children with meropenem from December 2017 to May 2018. RESULTS The reasonable rate of using this drug in the hospital was 77.16%. The coincidence rate of medication indication was 96.98%, the reasonable rate of combined medication was 89.22%, the correct usage rate was 100%, the rational rate of pathogen and efficacy evaluation was 73.28%, and the reasonable rate of assessment management was 99.57%. CONCLUSION Established clinical application evaluation criteria for meropenem can standardize the clinical utilization of such drugs. The clinical application of meropenem in this hospital is general. In response to existing problems, clinical pharmacists shall strengthen the special evaluation and monitoring of such drugs to promote safe and rational use of drugs.