Clinical Utility of Commercial Standardized Multi-chamber Bags and Customized Compound Total Parenteral Nutrition Admixture

OBJECTIVE To compare the clinical effects of commercial standardized multi-chamber bags(s-TPN) and customized total parenteral nutrition admixture(c-TPN) in adult hospitalized patients. METHODS The patients who were admitted to the Third Affiliated Hospital of Anhui Medical University(Hefei First People's Hospital) and supported by parenteral nutrition therapy were collected from June 1, 2017 to May 31, 2018. Collected data on hospitalization costs, surgery costs, total drug costs, nutrient medication costs, antibacterial medication costs, liver and kidney function indicators, electrolytes, blood glucose, hospital stay, and parenteral nutrition support time. So as to analyze and compare the clinical use effect of s-TPN and c-TPN. RESULTS Total of 50 patients were enrolled, including 25 in the s-TPN group and 25 in the c-TPN group. The clinical efficacy of the two groups was equivalent. The level of total bilirubin in c-TPN group was higher than that before medication, while in s-TPN group it was lower. There was a significant difference in parenteral nutrition support costs as wellc-TPN group (1 278.3±1 164.0) yuan, s-TPN group(3 396.4±3 313.2) yuan, P=0.004. CONCLUSION For adult hospitalized patients, there is no significant difference in the clinical effects of s-TPN and c-TPN. However, the effect of the c-TPN group on the level of Tbil in patients is smaller than that in the s-TPN group. There are significant differences in the cost of treatment between the two groups. It is suggesting that comprehensive consideration shall be given to the efficacy, adverse reactions, pharmacoeconomics and other data in the selection of different parenteral nutrition therapy plan.