Study for Drug-related Problems of Danshen Freeze-dried Powder for Injection in Clinical Application of Inpatients

OBJECTIVE To study drug-related problems(DRPs) of Danshen freeze-dried powder for injection in clinical application. METHODS Through the inpatient electronic medical records, medical records with Danshen freeze-dried powder for injection from January 2016 to September 2017 in the Third People's Hospital of Bengbu were surveyed statistically. Necessity, safety and effectiveness of Danshen freeze-dried powder for injection clinical application were studied with reference to DRPs of the Spanish Granada-Ⅱ Classification. RESULTS DRPs occurred in all 397 medical records with Danshen freeze-dried powder for injection. Danshen freeze-dried powder for injection accumulated generated 1 019 DRPs, including 413 DRP5, 317 DRP2, 227 DRP6, 62 DRP4. DRP5 mainly showed little solvent content, DRP2 mainly showed no indication, DRP6 mainly showed overdose medication, and DRP2 mainly showed insufficient treatment. CONCLUSION It is necessary for hospitals to develop intervention measure to enhance clinical safety, necessity and effectiveness of Danshen freeze-dried powder for injection in clinical application based on DRPs.