Effect of Wei Fuchun Tablet on Gastrointestinal Function in Functional Dyspesia Rats

OBJECTIVE To explore the improvement effect of Wei Fuchun tablet on gastrointestinal motility disorder. METHODS Functional dyspepsia(FD) rat model was established. Weight, diet, drinking, electrical activity of stomach muscle, gastric secretion, activity of gastric pepsin, the weight of liver and spleen, gastric pathology was used to observe the effect of Wei Fuchun tablet on FD rats. RESULTS The electrical activity of stomach muscle of FD rats in model group was obviously disordered, weight, diet, drinking and gastric pepsin activity were significantly decreased. After the treatment of Wei Fuchun tablet, the above phenomena were alleviated, weight, diet, drinking and gastric pepsin activity were significantly increased. CONCLUSION Wei Funchun tablet can improve the general state of the FD rats, inhibite gastric acid secretion and improve activity of gastric pepsin in model rats.