Progress in Research on Anti-tumor Mechanism of Apigenin

Apigenin is a natural flavonoid compound that is widely found in various fruits, vegetables and herbs, and has various biological effects such as anti-tumor, anti-oxidation and anti-inflammatory. Apigenin has significant anti-tumor effects, which can inhibit tumor cell proliferation, induce apoptosis of tumor cells, inhibit tumor invasion and metastasis, interfere with signal transduction of tumor cells, reverse drug resistance of cells, increase the sensitivity of chemotherapeutic drugs and anti-oxidation, etc. This review summarizes the main biological effects of apigenin and its anti-tumor mechanisms, and looks forward to the prospects of application and development of apigenin.