Meta Analysis of Efficacy of Compound Muniziqi Granule in Treatment of Chloasma

OBJECTIVE To evaluate the efficacy of Compound Muniziqi granule in the treatment of chloasma, and provide evidence-based reference for clinical treatment. METHODS CJFD, CNKI, VIP, Wanfang, EMbase, PubMed, and Cochrane library database were researched. The randomized controlled trials about Compound Muniziqi granule versus vitamin C plus vitamin E in the treatment of chloasma were collected. Meta analysis was performed on the selected experiment by using RevMan 5.3 software. RESULTS A total of 6 randomized controlled trials invoving 578 patients were included. The results of meta analysis indicated that the efficacy of Compound Muniziqi granule in the treatment of chloasma was significantly higher than that of vitamin C plus vitamin E group. CONCLUSION Compound Muniziqi granule is effective in the treatment of chloasma.