Effect of Simvastatin Combined with Diltiazem on Diabetic Nephropathy and Its Influence on Proteinuria

OBJECTIVE To investigate the clinical efficacy and proteinuria of simvastatin combined with diltiazem in the treatment of diabetic nephropathy patients. METHODS One hundred and twenty-eight cases of diabetic nephropathy patients, were divided into observation group and control group randomly. The control group were treated with diet, exercise and simvastatin, while the observed group treated with diet, exercise, simvastatin combined with diltiazem. RESULTS After the treatment, condition of two groups were improved significantly, and the level of blood glucose, fasting blood glucose, postprandial 2H blood glucose, Glomerular filtration rate, proteinuria changes in the observation group were significantly better than the control group (P<0.05). CONCLUSION After diabetic nephropathy patients treated with simvastatin combined with diltiazem, it can improve patients' quality of life and have good application value in the treatment of such patients.