Effects of Dexmedetomidine Combined with Parecoxib Sodium on Postoperative Pain in Elderly Patients with Colorectal

OBJECTIVE To investigate the effect of dexmedetomidine combined with parecoxib sodium on postoperative pain in elderly patients with colorectal cancer. METHODS Sixty-one elderly patients over 60 years old with colorectal cancer were randomly divided into two groups, the control group(31 cases):patients were treated with dexmedetomidine treatment; the experimental group(30 cases):patients were treated with dexmedetomidine combined with parecoxib treatment. To observe and compare the effects of 2 medication schemes on elderly patients after colorectal cancer surgery. RESULTS The postanesthesia care unit(PACU) residence time of the experimental group was shorter than the control group. According to the patients' visual analogue score (VAS) score after 2, 12, and 24 h, the level of VAS score in the 2 groups decreased with time, and the VAS score of the experimental group was lower. The total number of patient controlled analgesia (PCA) in the experimental group was lower than that in the control group, and the analgesic effect was better, the differences were statistically significant(P<0.05). In terms of emotion, the scores of anger scale after 48 h and 96 h were lower in the experimental group(P<0.05). In addition, compared with the the control group, patients' satisfaction score was higher and the recovery time of postoperative intestinal peristalsis was even shorter in the experimental group, and the difference were statistically significant(P<0.05). CONCLUSION the control of deemethomidine combined with parecoxib sodium on postoperative pain in elderly patients with colorectal cancer is better, it is recommended for clinical use.