Study on the Quality Standard for Urea Cream

OBJECTIVE To establish and improve the quality standard of Urea cream. METHODS The effective constituent of Urea cream were qualitative identified according to the methods in Chinese Pharmacopoeia (2015 edition) and its content was determined by DMAB color-test. RESULTS The qualitative identifications of urea were specific. The liner range of urea was 0.036 78-0.085 81 mg·ml^-1(r=0.999 5), its average recovery were 98.19% and RSD was 0.24%(n=9). CONCLUSION The method is simple and practical, the result is accurate and reliable and it can be used to control the quality of Urea cream.