Clinical Study on Effect of Buqihuoxue Prescription in Treating Ethambutol-induced Optic Neuropathy with Mecobalamin

OBJECTIVE To observe clinical effect of Buqihuoxue prescription in treating ethambutol-induced optic neuropathy combined with mecobalamin. METHODS Forty-eight ethambutol-induced optic neuropathy patients who were received in outpatient department of ophthalmology in Hangzhou Red Cross Hospital from June 2014 to June 2016 were randomly divided into two groups(treatment group and control group), 25 patients in treatment group were treated with Buqihuoxue prescription and mecobalamin, 23 patients in control group were treated with mecobalamin. Compared and assessed the clinical curative effect between the two groups after treatment with a mean follow-up of three months. RESULTS Total effective rate in the treatment group and the control group was 96.00% and 73.91%. There were significant differences between the two groups(X²=4.691, P<0.05). CONCLUSION The treatment for ethambutol-induced optic neuropathy used by Buqihuoxue prescription with mecobalamin is more satisfied and effective than that with conventional western medicine.