Study on the Safety Test of Sodium Tanshinone Ⅱ_A Sulfonate for Injection

OBJECTIVE To establish the safety test for sodium tanshinone Ⅱ_A sulfonate for injection. METHODS Testing items of abnormal toxicity and depressor substances and their limiting values were set separately. The correlative experiments were carried out based on the methods from Chinese Pharmacopoeia(2015 edition) general chapters. RESULTS The limiting values of abnormal toxicity test was 40.91 mg·kg^-1 and depressor substances test was 1 mg·kg^-1. CONCLUSION This study provides experimental basis for the improved quality standard of sodium tanshinone Ⅱ_A sulfonate for injection.