Research Progress of Methods for Preparing Cisatracurium Besylate

Cisatracurium besylate is a classic nondepolarizing neuromuscular blocking agent. Its synthetic methods have been widely concerned. It is analyzed the synthetic process of cisatracurium besylate and summarizes synthetic routes and technology by searching the references and patents from 1982 to 2015, discussing low rate of synthetic routes of cisatracurium besylate. Its separation of chiral drugs have wider development prospect.