Chemical Constituents of Ethyl Acetate Fraction From Patrinia Scabra

OBJECTIVE To study the chemical constituents of ethyl acetate fraction from Patrinia scabra Bunge. METHODS Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. RESULTS Eleven compounds were isolated and purified. Their structures were identified as 7α-O-methylmorroniside(1), 7β-O-methylmorroniside(2), 1-octanol(3), 2,3-nonyl olefin(4), lariciresinol (5), Jatamanin J(6), lariciresinol-4-O-β-D-glucopyrano-side(7), patriscabrol(8) Jatamanin A(9), Scabroside A(10), daturic acid 2, 3-dihydroxyopropyl(11). CONCLUSION Compounds 1-4 are isolated from this plant for the first time, the compound 3 and 4 were isolated from Patrinia Juss. for the first time.