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引用本文:姜丽丽.137例中药注射剂ADR的综合分析及安全用药对策[J].中国现代应用药学,2009,(4):340-344.
JIANG Lili.The Analysis and Countermeasure of 137 Case Reports to ADR Caused by Chinese Traditional Medicine Injection[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,(4):340-344.
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137例中药注射剂ADR的综合分析及安全用药对策
姜丽丽
作者单位
姜丽丽  
摘要:
目的了解本院中药注射剂不良反应(ADR)发生情况并探讨其发生的可能因素和相应的对策。方法采用回顾性研究方法,对浙江省中医院2006~2007年收集的137例中药注射剂ADR进行归纳分析。 结果中药注射剂致不良反应的临床表现多种多样,以皮肤过敏、药物热最常见。皮肤过敏有60例占43.80%,药物热有28例占20.43% 。涉及24个品种,其中双黄连、刺五加、痰热清3种注射剂诱发的不良反应为多,共49例占35.77%。结论中医院应提倡合理使用中药注射剂,加强中药注射剂不良反应的预防、监测及警戒,保障患者用药的安全性。
关键词:  中药注射剂  不良反应  因素分析  对策
DOI:
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基金项目:
The Analysis and Countermeasure of 137 Case Reports to ADR Caused by Chinese Traditional Medicine Injection
JIANG Lili
Abstract:
OBJECTIVE To understand the occurrence circumstance for adverse drug reactions (ADR) caused by Chinese traditional medicine injections, and investigate the possible factors with correlated countermeasure. METHODS Used retrospective study,137 ADR reports collected at Chinese traditional medicine hospital of Zhejiang from 2006 to 2007 were statistically analyzed. RESULTS ADR were manifested variously at clinic,mainly as skin allergic reaction and fever caused by medicine,60 cases(43.80%) and 28 cases (20.43%),respectively.Total ADR involved in 24 kinds of Chinese traditional medicine injections, among them Shuang-huang-lian, Ci-wu-jia, Tan-re-qing injections induced 49 cases (35.77%).CONCLUSION The hospital should promote the rational use of Chinese traditional medicine injections, and strengthen the prevention, monitoring and wathfulness of ADR, to ensure the safety of clinical medication.
Key words:  Chinese traditional medicine injection  adverse drug reactions  analysis of factor  countermeasure
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