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引用本文:余靓平,杨勇,欧阳华,陈凌,张长泽.1例极低出生体质量儿伴坏死性小肠结肠炎营养支持治疗的药学监护[J].中国现代应用药学,2020,37(3):354-357.
YU Liangping,YANG Yong,OUYANG Hua,CHEN Ling,ZHANG Changze.Pharmaceutical Care of Clinical Nutrition Treatment for a Very Low Birth Weight Infant with Necrotizing Enterocolitis[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(3):354-357.
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1例极低出生体质量儿伴坏死性小肠结肠炎营养支持治疗的药学监护
余靓平1, 杨勇2,3, 欧阳华1, 陈凌4, 张长泽1
1.厦门大学附属中山医院, 药学部, 福建 厦门 361004;2.四川省医学科学院·3.四川省人民医院药学部, 成都 610072;4.厦门大学附属中山医院, 儿科, 福建 厦门 361004
摘要:
目的 通过对1例极低出生体质量儿并发坏死性小肠结肠炎(necrotizing enterocolitis,NEC)患儿营养支持方案的优化干预和药学监护,探讨临床药师在营养支持治疗中发挥的作用。方法 对患儿初始肠外营养支持方案进行优化,在患儿并发NEC及出现肠外营养相关的高甘油三酯血症时,及时对营养支持方案的调整进行干预。结果 出生后24 h内给予氨基酸是安全的。当患儿出现NEC时予以禁食,全肠外营养支持;当出现高甘油三酯血症时应减少脂肪乳用量。结论 患儿营养支持方案的制定与调整做到了个体化,使营养支持治疗达到较好的效果。
关键词:  极低出生体质量儿  新生儿坏死性小肠结肠炎  营养支持  药学监护
DOI:10.13748/j.cnki.issn1007-7693.2020.03.019
分类号:R969.3
基金项目:
Pharmaceutical Care of Clinical Nutrition Treatment for a Very Low Birth Weight Infant with Necrotizing Enterocolitis
YU Liangping,YANG Yong,OUYANG Hua,CHEN Ling,ZHANG Changze
1.Zhongshan Hospital Affiliated to Xiamen University, Department of Pharmacy, Xiamen 361004, China;2.Department of Pharmacy, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China;3.Zhongshan Hospital Affiliated to Xiamen University, Department of Pediatrics, Xiamen 361004, China
Abstract:
OBJECTIVE To explore the role of clinical pharmacists in nutrition support treatment by optimizing intervention and providing pharmaceutical care for the nutritional supportive program for a very low birth weight infant with necrotizing enterocolitis(NEC). METHODS The initial parenteral nutrition support program for the very low birth weight infant was optimized, and the nutritional support program was timely adjusted when the infant was complicated with NEC and hypertriglyceridemia associated with parenteral nutrition. RESULTS It was safe to give amino acids in 24 h after birth. When the infant was diagnosed with NEC, she or he should be fasted and supported with parenteral nutrition totally instead. When symptom of high triglycerides developed, the amount of fat emulsion should be reduced. CONCLUSION The formulation and adjustment of infant's nutritional support program shall be individualized to achieve a more satisfactory therapeutic effect.
Key words:  very low birth weight infant  neonatal necrotizing enterocolitis  nutritional support  pharmaceutical care
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