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引用本文:魏娟,祝宇,余世荣,周灿,张晓燕.空心柴胡的生药学研究[J].中国现代应用药学,2020,37(1):35-39.
WEI Juan,ZHU Yu,YU Shirong,ZHOU Can,ZHANG Xiaoyan.Pharmacognostical Study on Bupleurum Longicaule Var. Franchetii[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(1):35-39.
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空心柴胡的生药学研究
魏娟, 祝宇, 余世荣, 周灿, 张晓燕
十堰市人民医院 湖北医药学院附属人民医院药学部, 湖北 十堰 442000
摘要:
目的 对伞形科植物空心柴胡(Bupleurum longicaule var.Franchetii)进行生药学研究。方法 本研究采用基源鉴别、药材性状鉴别、显微鉴别对空心柴胡鉴别特征进行研究;薄层色谱结合HPLC对其有效成分进行定性定量鉴别。结果 空心柴胡药材性状特征、粉末、根及根茎横切面显微特征均较明显,薄层色谱展开分离结果较好,其有效活性成分柴胡皂苷a、柴胡皂苷d的含量较高。结论 本研究可为空心柴胡的品种鉴别、质量评价、质量标准的制订及进一步开发利用提供一定的参考。
关键词:  空心柴胡  生药学  柴胡皂苷a  柴胡皂苷d  高效液相色谱法
DOI:10.13748/j.cnki.issn1007-7693.2020.01.007
分类号:R286.0
基金项目:十堰市科学技术研究与开发项目(18Y72,17K73)
Pharmacognostical Study on Bupleurum Longicaule Var. Franchetii
WEI Juan, ZHU Yu, YU Shirong, ZHOU Can, ZHANG Xiaoyan
Department of Pharmacy, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China
Abstract:
OBJECTIVE To make pharmacognostical study on the umbelliferae Bupleurum longicaule var. Franchetii. METHODS In this study, the identification characteristics of Bupleurum longicaule var. Franchetii were studied by primary appraisement, medicinal material identification and microscopical identification. In addition, TLC combined with HPLC were adopted to identify its active ingredients qualitatively and quantitatively. RESULTS The characteristics of medicinal properties, the microscopic characteristics of the powder and the transverse section of radix and rhizoma were all obvious, and the result of TLC was good. The effective active components of saikosaponin a and saikosaponin d had high content. CONCLUSION This study can provide reference for the identification, quality evaluation, quality standard formulation and further development and utilization of Bupleurum longicaule var. Franchetii.
Key words:  Bupleurum longicaule var. Franchetii  pharmacognosy study  saikosaponin a  saikosaponin d  HPLC
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