| 引用本文: | 王庆芬,杨育儒,沈秋莲,张荣.枇芩颗粒剂体外抑制金黄色葡萄球菌和痤疮丙酸杆菌的作用[J].中国现代应用药学,2015,32(12):1457-1460. |
| WANG Qingfen,YANG Yuru,SHEN Qiulian,ZHANG Rong.Bacteriostatic Action of Piqin Granules Against Staphylococcus Aureus and Propionibacterium Acnes in Vitro[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(12):1457-1460. |
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| 摘要: |
| 目的 研究枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌的体外抑制作用。方法 采用滤纸片或牛津杯的琼脂扩散法观察枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌的体外抑菌作用，同时定量测定枇芩颗粒剂对这2种菌的最低抑菌浓度。结果 枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌均有明显抑菌作用，对金黄色葡萄球菌最低抑菌浓度为0.05 g·mL-1，对痤疮丙酸杆菌最低抑菌浓度为0.10 g·mL-1。结论 枇芩颗粒剂对金黄色葡萄球菌和痤疮丙酸杆菌均具有明显的抑制作用。 |
| 关键词: 枇芩颗粒剂 金黄色葡萄球菌 痤疮丙酸杆菌 体外抑菌 |
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| 基金项目:中国人民解放军第一七五医院青年苗圃基金资助项目(13Y016) |
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| Bacteriostatic Action of Piqin Granules Against Staphylococcus Aureus and Propionibacterium Acnes in Vitro |
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WANG Qingfen, YANG Yuru, SHEN Qiulian, ZHANG Rong
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Department of Pharmacy, 175 Hospital of PLA, The Affiliated Southeast Hospital of Xiamen University, Zhangzhou 363000, China
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| Abstract: |
| OBJECTIVE To study effect of Piqin granules on bacteriostatic action against Staphylococcus aureus and Propionibacterium acnes in vitro. METHODS The effect on bacteriostatic action against Staphylococcus aureus and Propionibacterium acnes were cultured by plating method and oxfordcup, and then by test tube continuously dilution in order to observe their minimal inhibitory concentration(MIC). RESULTS Piqin granules were highly sensitive to Staphylococcus aureus and Propionibacterium acnes in vitro. The MIC was 0.05 g·mL-1 against Staphylococcus aureus; and the MIC was 0.10 g·mL-1 against Propionibacterium acnes. CONCLUSION Piqin granules show satisfactory bacteriostatic action against the Staphylococcus aureus and Propionibacterium acnes. |
| Key words: Piqin granules Staphylococcus aureus Propionibacterium acnes bacteriostatic action in vitro |
