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引用本文:范峥,吴晓平,郭桂明,刘洋,常馨予,胡永芳.嗜麦芽窄食单胞菌的抗感染治疗1例及文献复习[J].中国现代应用药学,2015,32(10):1250-1253.
FAN Zheng,WU Xiaoping,GUO Guiming,LIU Yang,CHANG Xinyu,HU Yongfang.Anti-infection Treatment of Stenotrophomonas Maltophilia: A Case Report and Review of the Literature[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(10):1250-1253.
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嗜麦芽窄食单胞菌的抗感染治疗1例及文献复习
范峥1,2, 吴晓平1,3, 郭桂明2, 刘洋2, 常馨予2, 胡永芳1
1.北京大学第三医院,北京 100191;2.首都医科大学附属北京中医医院,北京 100010;3.新疆医科大学第二附属医院,乌鲁木齐 830028
摘要:
目的 为嗜麦芽窄食单胞菌的抗感染治疗提供方案,达到合理用药的目的。方法 报道、分析1例案例,同时查阅相关文献进行综述讨论。结果 患者使用头孢吡肟、亚胺培南西司他丁联合利奈唑胺治疗后,感染控制不理想,更换为头孢哌酮舒巴坦联合莫西沙星抗感染治疗,患者逐渐好转,检索相关研究并进行分析,该治疗方案是可行的。结论 头孢哌酮舒巴坦联合莫西沙星治疗嗜麦芽窄食单胞菌感染疗效好、可行,但是否为最优方案有待进一步临床试验。
关键词:  嗜麦芽窄食单胞菌  抗感染治疗  头孢哌酮舒巴坦  莫西沙星
DOI:
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Anti-infection Treatment of Stenotrophomonas Maltophilia: A Case Report and Review of the Literature
FAN Zheng1,2, WU Xiaoping1,3, GUO Guiming2, LIU Yang2, CHANG Xinyu2, HU Yongfang1
1.Peking University Third Hospital, Beijing 100191, China;2.Beijing Hospital of TCM Affiliated to Capital Medical University, Beijing 100010, China;3.The Second Affilated Hospital of Xinjiang Medical University, Urumqi 830028, China
Abstract:
OBJECTIVE To provide an anti-infection therapeutic regimen of Stenotrophomonas maltophilia and promote rational administration. METHODS A case of anti-infection treatment of Stenotrophomonas Maltophilia was reported and analyzed. Relevant literature was reviewed. RESULTS By using cefepime, imipenem cilastatin combined with linezolid, the patient’s infection was not well controlled. Later cefoperazone sulbactam combined with moxifloxacin was used, the patient gradually improved. The available literature suggested that this therapeutic regimen was feasible. CONCLUSION Using cefoperazone sulbactam combined with moxifloxacin has curative an effect on the infection of Stenotrophomonas maltophilia, but wheter it’s optimal program is difficult to assess whether it is the optimal scheme needs further clinical experiments.
Key words:  Stenotrophomonas maltophilia  anti-infective therapy  cefoperazone sulbactam  moxifloxacin
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