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引用本文:章晔,方洁.1例人感染H7N9禽流感的药学监护[J].中国现代应用药学,2015,32(3):362-366.
ZHANG Ye,FANG Jie.Pharmaceutical Care to an H7N9 Influenza Patient[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(3):362-366.
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1例人感染H7N9禽流感的药学监护
章晔1, 方洁2
1.浙江中医药大学附属第二医院药剂科,杭州 310005;2.上海交通大学医学院附属瑞金医院药剂科,上海 200025
摘要:
目的 探讨对H7N9流感病毒可能有效的治疗方案以及药学监护思路。方法 对临床药师参与的1例人感染H7N9禽流感的药物治疗全过程进行药学监护,并总结分析。结果 临床药师对患者的抗病毒、抗细菌和抗炎治疗过程开展药学监护,并对期间出现的肝功能损害进行分析和探讨。结论 神经氨酸酶抑制剂可能有效,静注人免疫球蛋白的作用不可忽视,糖皮质激素的使用仍有争议。临床药师必须培养临床思维能力,药学监护以药物疗效为首要出发点,密切关注用药细节,警惕药物不良反应。
关键词:  H7N9流感病毒  神经氨酸酶抑制剂  静注人免疫球蛋白  药物性肝损伤
DOI:
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基金项目:
Pharmaceutical Care to an H7N9 Influenza Patient
ZHANG Ye1, FANG Jie2
1.Department of Pharmacy, the Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310005, China;2.Department of Pharmacy, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Abstract:
OBJECTIVE To discuss the effective therapeutic regimen of H7N9 influenza and the train of thought of pharmaceutical care. METHODS Clinical pharmacist implement the whole pharmaceutical care to an H7N9 influenza patient, and analyze and summarize. RESULTS Clinical pharmacist provided pharmaceutical care to the patient through anti-viral, anti-bacteria and anti-inflammatory treatment. Analysis and discussion the liver function injury during the treatment. CONCLUSION Neuraminidase inhibitors(NAI) may be effective, and immunoglobulin(IVIG) can not be ignored, and the use of glucocorticoid is still controversial. Clinical pharmacists must cultivate the clinical thinking ability.Pharmaceutical care must take the curative effect as the primary starting point. Clinical pharmacists must pay close attention to the medication details and adverse drug reaction.
Key words:  H7N9 influenza virus  nueraminidase inhibitor(NAI)  intravenous immunoglobulin(IVIG)  drug-induced liver injury
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