β-受体阻滞剂治疗婴幼儿血管瘤的不良反应及防治对策

李健和; 胡焰; 赵子影; 易利丹; 刘新义; 彭六保<sup>*</sup>

引用本文:	李健和,胡焰,赵子影,易利丹,刘新义,彭六保.β-受体阻滞剂治疗婴幼儿血管瘤的不良反应及防治对策[J].中国现代应用药学,2013,30(9):1022-1027.
	LI Jianhe,HU Yan,ZHAO Ziying,YI Lidan,LIU Xinyi,PENG Liubao.Adverse Reactions and Prevention Countermeasures of Beta-blockers Treatment for Infantile Hemangiomas[J].Chin J Mod Appl Pharm(中国现代应用药学),2013,30(9):1022-1027.

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β-受体阻滞剂治疗婴幼儿血管瘤的不良反应及防治对策
李健和¹, 胡焰², 赵子影², 易利丹¹, 刘新义¹, 彭六保¹
1.中南大学湘雅二医院药学部，长沙 410011;2.中南大学药学院，长沙 410013

摘要:

在PubMed、Medline、EMBASE/EM、IPA及CNKI等数据库中对2008年5月—2012年9月有关β-受体阻滞剂治疗婴幼儿血管瘤临床试验中出现的不良反应的相关文献进行检索，综述了β-受体阻滞剂治疗婴幼儿血管瘤的不良反应及防治对策，供临床和新药研发参考，以促进临床安全合理用药，为进一步开发β-受体阻滞剂的新适应症和新制剂新剂型提供依据。

关键词: β-受体阻滞剂婴幼儿血管瘤临床试验不良反应防治对策

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Adverse Reactions and Prevention Countermeasures of Beta-blockers Treatment for Infantile Hemangiomas

LI Jianhe¹, HU Yan², ZHAO Ziying², YI Lidan¹, LIU Xinyi¹, PENG Liubao¹

1.Department of Pharmacy, the Second Xiangya Hospital of Central South University, Changsha 410011, China;2.Pharmacy of Central South University, Changsha 410013, China

Abstract:

This paper reviewed the adverse reactions and prevention countermeasures of beta-blockers treatment for infantile hemangiomas. A search in PubMed, Medline, EMBASE/EM, IPA, CNKI and etc electronic database for all articles about adverse reactions in clinical trails of the beta-blockers treatment for infantile hemangiomas from May 2008 to September 2012 was conducted. This review could provide reference for clinical applications and development of new drug to promote rational use and clinical safety of the drug and then offer basis for the development of new indication and new formulation of beta-blockers.

Key words: beta-blockers infantile hemangiomas clinical trials adverse reactions prevention countermeasures