| 引用本文: | 涂银萍,王久伶,王晶.C反应蛋白对社区获得性肺炎的诊断价值[J].中国现代应用药学,2012,29(12):1147-1149. |
| TU Yinping,WANG Jiuling,WANG Jing.Diagnosis Value of C-reactive Protein in Community Acquired Pneumonia[J].Chin J Mod Appl Pharm(中国现代应用药学),2012,29(12):1147-1149. |
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| 摘要: |
| 目的 探讨C反应蛋白(CRP)对社区获得性肺炎(CAP)的诊断价值。方法 对笔者所在医院发热门诊2011年2月—2012年1月接诊的患者进行随机抽样，对抽样获得的611例患者进行回顾性分析。CRP采用QuikRead CRP快速分析仪检测。结果 611例患者中CRP增高394例(占64.5%)，其中肺炎患者占16.50%(65/394)，而在CRP正常的217例患者中，肺炎占4.15%(9/217)，前者明显高于后者(P＜0.05)。当CRP值＞30 mg·L-1时，约有1/5的患者诊断为肺炎，CRP值＞50 mg·L-1时，约有1/4的患者诊断为肺炎。CRP值增高对肺炎诊断的敏感性为87.84%，阳性预测值是16.50%，阴性预测值是95.85%。结论 在发热门诊，CRP水平与CAP的诊断有一定的相关性，而且阴性预测值较高。 |
| 关键词: 社区获得性感染 肺炎 C反应蛋白 |
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| Diagnosis Value of C-reactive Protein in Community Acquired Pneumonia |
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TU Yinping, WANG Jiuling, WANG Jing
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Department of Infectious Diseases, Xuanwu Hospital of the Capital University of Medical Sciences, Beijing 100053, China
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| Abstract: |
| OBJECTIVE To evaluate the diagnosis value of C-reactive protein(CRP) in patients with community acquired pneumonia(CAP). METHODS A retrospective study was performed on 611 randomly selected patients in fever clinic of Xuanwu Hospital during one year(2011-02-01-2012-01-31). All patients were detected by the QuikRead of CRP. RESULTS In 611 patients, CRP was elevated(>10 mg·L-1) in 394 cases (accounting for 64.5%) in which patients with pneumonia accounted for 16.50%, while 217 patients with normal CRP level(≤10 mg·L-1) had low proportion of CAP patients (accounting for 4.15%). There was significant difference(P<0.05). When CRP levels >30 mg·L-1, there were about 1/5 patients diagnosed with CAP, and CRP levels >50 mg·L-1, there were about 1/4 patients diagnosed with CAP. The sensitivity of CRP on the diagnosis of pneumonia was 87.84%. Total positive predictive, negative predictive value of CRP rapid test was 16.50% and 95.85%, respectively. CONCLUSION In fever clinic, the levels of CRP show a significant correction with the diagnosis of CAP, and negative predictive value of CRP testing is higher. |
| Key words: community acquired infections pneumonia C-reactive protein |
