1例妊娠期铜绿假单胞菌宫腔感染的病例分析与药学监护

汪凤梅; 孙冬黎; 毕娟; 王卓

引用本文:	汪凤梅,孙冬黎,毕娟,王卓.1例妊娠期铜绿假单胞菌宫腔感染的病例分析与药学监护[J].中国现代应用药学,2021,38(15):1860-1864.
	WANG Fengmei,SUN Dongli,BI Juan,WANG Zhuo.Analysis and Pharmaceutical Care of A Case of Intra-amniotic Infection with Pseudomonas Aeruginosa During Pregnancy[J].Chin J Mod Appl Pharm(中国现代应用药学),2021,38(15):1860-1864.

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1例妊娠期铜绿假单胞菌宫腔感染的病例分析与药学监护
汪凤梅¹, 孙冬黎¹, 毕娟², 王卓²
1.浙江大学医学院附属妇产科医院药剂科, 杭州 310006;2.海军军医大学第一附属医院药学部, 上海 200433

摘要:

目的通过对1例胎膜早破、宫腔铜绿假单胞菌感染患者的抗感染治疗分析，探讨抗铜绿假单胞菌治疗过程中宫颈局部治疗初始效果不佳的原因和应对策略。方法临床药师参与患者药物治疗方案的调整，结合目前铜绿假单胞菌的耐药情况和患者自身情况，建议临床医师调整抗感染治疗方案。结果患者改用注射用哌拉西林钠他唑巴坦钠治疗1周后，临床症状显著好转。结论临床药师参与临床治疗，协助临床医师优化治疗方案，使患者用药更加安全、有效和合理。

关键词: 胎膜早破宫腔感染铜绿假单胞菌注射用亚胺培南西司他丁钠药学监护

DOI：10.13748/j.cnki.issn1007-7693.2021.15.011

分类号:R969.4

基金项目:

Analysis and Pharmaceutical Care of A Case of Intra-amniotic Infection with Pseudomonas Aeruginosa During Pregnancy

WANG Fengmei¹, SUN Dongli¹, BI Juan², WANG Zhuo²

1.Department of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China;2.Department of Pharmacy, First Affiliated Hospital, Naval Medical University, Shanghai 200433, China

Abstract:

OBJECTIVE To report a case of antibiotic therapy in a patient with premature rupture of membranes(PROM) and intra-amniotic infection(IAI) with Pseudomonas aeruginosa(PA), discussed the reason of the poor initial effect of the local cervical treatment and the strategy of treatment in PA antibiotic therapy. METHODS Clinical pharmacists participated in the adjustment of patients' drug treatment plan, considering the current resistance of PA and the patient's own situation, clinical pharmacists suggested physicians to adjust the strategy of drug treatment. RESULTS After piperacillin sodium/tazobactam was applied for a week, the symptoms of the patient were obviously improved. CONCLUSION Clinical pharmacists participate in the clinical treatment, provide a reasonable clinical treatment program with physicians, can make the medication more safe, effective and reasonable for patients.

Key words: premature rupture of membranes intra-amniotic infection Pseudomonas aeruginosa imipenem cilastatin pharmaceutical care