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引用本文:王佰涛,杨文玲,陈国参,刘德海,杨书豪.肉桂提取物及其活性成分对2型糖尿病改善作用的研究进展[J].中国现代应用药学,2021,38(10):1269-1274.
WANG Baitao,YANG Wenling,CHEN Guocan,LIU Dehai,YANG Shuhao.Research Progress on the Improving Effect of Cinnamon Extract and Its Active Components on Type 2 Diabetes[J].Chin J Mod Appl Pharm(中国现代应用药学),2021,38(10):1269-1274.
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肉桂提取物及其活性成分对2型糖尿病改善作用的研究进展
王佰涛, 杨文玲, 陈国参, 刘德海, 杨书豪
河南省科学院生物研究所有限责任公司, 郑州 450008
摘要:
糖尿病作为一种复杂的代谢疾病,严重威胁着人类的健康,而2型糖尿病因其发病原因复杂,一直以来备受关注。现代研究发现肉桂提取物及其活性成分具有抗菌、抗肿瘤等多种药理作用,药用价值极高,对2型糖尿病可以产生很好的改善作用,能够从多方面改善2型糖尿病的症状,临床研究表明肉桂提取物及其活性成分对于改善胰岛素抵抗和脂质代谢紊乱效果良好。本文将结合肉桂提取物及其活性成分的临床研究和基础研究从降血糖、抑制糖基化终产物形成、阻止糖尿病并发症等方面对其改善作用进行论述,以期为肉桂提取物及其活性成分在临床上对2型糖尿病的治疗提供帮助。
关键词:  2型糖尿病  肉桂提取物  糖基化终产物  改善作用
DOI:10.13748/j.cnki.issn1007-7693.2021.10.022
分类号:R285.5
基金项目:河南省科学院科技开放合作项目(200905013)
Research Progress on the Improving Effect of Cinnamon Extract and Its Active Components on Type 2 Diabetes
WANG Baitao, YANG Wenling, CHEN Guocan, LIU Dehai, YANG Shuhao
Institute of Biology Co., Ltd., Henan Academy of Science, Zhengzhou 450008, China
Abstract:
Diabetes, as a complex metabolic disease, is a serious threat to human health, while type 2 diabetes has attracted much attention because of its complex causes.Modern studies have found that cinnamon extract and its active components have a variety of pharmacological effects, such as antibacterial, anti-tumor and so on.It can improve type 2 diabetes and improve the symptoms of type 2 diabetes in many ways.Clinical studies have shown that cinnamon extract and its active components are effective in improving insulin resistance and lipid metabolism disorders.Combined with the clinical and basic research of cinnamon extract and its active components, this paper discusses its improvement effect from the aspects of lowering blood sugar, inhibiting the formation of advanced glycation end products and preventing diabetic complications, in order to provide help for the clinical treatment of type 2 diabetes.
Key words:  type 2 diabetes  cinnamon extract  advanced glycation end products  improvement effect
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