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| 摘要: |
| 目的探讨金钱草颗粒剂的质量标准。方法采用TLC对金钱草颗粒剂处方中的柴胡、延胡索及大黄进行定性鉴别；采用HPLC对其主药金钱草中的槲皮素进行定量分析。结果该方法定性鉴别薄层色谱特征明显，专属性强；样品中槲皮素在1.896 0～30.336 0 μg·mL-1内线性关系良好(r=0.999 8)，平均回收率为97.73%，RSD=1.34%。结论用该方法作定性、定量分析简便、快速、专属性强，可有效控制制剂的质量。 |
| 关键词: 金钱草 颗粒剂 薄层色谱法 高效液相色谱法 槲皮素 |
| DOI： |
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| Studies on Quality Standard of Herba Lysimachiae |
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SHEN Defeng，JIAO Yan
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| Abstract: |
| OBJECTIVE Study on quality standards for Herba Lysimachiae granules. METHODS Chinese thorowax root, corydalis and Rhubarb of Herba Lysimachine granules prescription were identified by TLC. The content of quercetin in Herba Lysimachine granules was determined by HPLC. RESULTS The chromatogram for identification by TLC was distinct and hightly specific. A good linear relationship was obtained in a range of quercetin concentrations from 1.896 0 g·mL-1 to 30.336 0 g·mL-1(r=0.999 8). The average recovery was 97.73%, RSD was 1.34%. CONCLUSION The method is simple, rapid and specific, and can be used for the quality control of the mixture. |
| Key words: Herba Lysimachiae granules TLC HPLC quercetin |
